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Which of the signaling receptors are generally activated by dimerization induced by binding to two sites...

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Biology

Which of the signaling receptors are generally activated bydimerization induced by binding to two sites on their ligand?

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ANSWER RECEPTOR WHICH ARE ACTIVATED BY DIMERIZATION INCLUDE Receptor Tyrosine Kinase RTK Contains intrinsic tyrosine kinase activity EGFR VEGFR Growth factors such as insulin epidermal growth factor EGF and plateletderived growth factor bind to the extracellular domains of transmembrane receptors that have tyrosine kinase domains present within their intracellular domainsThe receptor tyrosine kinase is monomeric and enzymatically inactive in the absence of the growth factor The binding of EGF to the extracellular domain causes the receptor to dimerize and    See Answer
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