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What sorts of adjustments would P. aeruginosa have to make in adapting successfully to the human...

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Biology

What sorts of adjustments would P. aeruginosa have to make inadapting successfully to the human lung?

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Pseudomonas aeruginosa a gram negative bacterium is opportunistic pathogen that can cause acute and chronic lung infections in immunocompromised lungs P aeruginosa has a reservoir in upper respiratory tract where they reside in paranasal sinuses and nasopharynx Adaptation in the upper respiratory tract is required for this organism to infect the lungs later on The P aeruginosa PA will adapt in the lungs by reducing production of virulence factors which results in reduced invasiveness This allows the bacterium to persist in the lungs without being killed by immune cells PA will evade host recognition of its flagellar antigens Flagellin    See Answer
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