What are some possible errors which affect %yield in the column chromatography experiment? (No TLC)

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Chemistry

What are some possible errors which affect %yield in the columnchromatography experiment? (No TLC)

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Sometimes the compound are very polar and if they are not predissolved properly in the silica gel it may recrystalize in the column and will take much longer time to come So when we stop the column by analyzing tlc the product    See Answer
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