Question 1 (1 point) Saved Imagine that you are working with DNA sequences of soluble proteins (not membrane...

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Biology

Question 1 (1 point)
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Imagine that you are working with DNA sequences of solubleproteins (not membrane proteins) and have the technology togenetically engineer/alter the existing sequence and you canexpress this particular protein in a yeast cell model.
You also have the power to track and visualize where thegenetically engineered proteins traffic in your modelsystem.Â Â
You engineer an ER signal sequence to the amino-terminal end ofa normally cytosolic protein.Â Â Â
Which best describes the fate of this protein?
Question 1 options:
A. The protein is translocated through the ER membranetranslocon channel, Nâ€™ end first
B. The protein is translocated through the ER membranetranslocon channel, Câ€™ end first
C. The protein remains in the cytosol
Question 2 (1 point)
You engineer an ER signal sequence to the carboxyl-terminal endof a normally cytosolic protein.Â Â Â
Which best describes the fate of this protein?
Question 2 options:
A. The protein is translocated through the ER membranetransloconchannel, Nâ€™ end first
B. The protein is translocated through the ER membranetransloconchannel, Câ€™ end first
C. The protein remains in the cytosol

Answer & Explanation Solved by verified expert

4.3 Ratings (757 Votes)

1 proteins with N terminal signal sequence will be translated to the ER lumen the ribosome in the cytosol start to translate the mRNA once the signal sequence is produced in See Answer

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	A. The protein is translocated through the ER membranetranslocon channel, Nâ€™ end first
	B. The protein is translocated through the ER membranetranslocon channel, Câ€™ end first
	C. The protein remains in the cytosol