Proteins destined for the nucleus contain a \"nuclear localization signal\" or NLS. How does the the...

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Medical Sciences

Proteins destined for the nucleus contain a \"nuclearlocalization signal\" or NLS. How does the the NLS direct theprotein to the nucleus?
Proteins that contain a NLS are allowed to freely diffuse intothe nucleus
Proteins that contain a NLS interact with a receptor on thesurface of the nuclear membrane
Proteins that contain a NLS interact with a transport systemthat is powered by the hydrolysis of GTP
Proteins that contain a NLS are synthesized by ribosomesattached to the nuclear membrane and they are extruded into thenucleus
All of the following are second messengers usedinside the cell for signalingexcept:
cAMP
Inositol phosphates
Adrenalined
Ca⁺⁺
You have identified a new gene in the superchick stimulatedgrowth factor pathway. Interestingly, both copies of the gene mustbe mutant in order for the phenotype of excessive growth to appear.Which of the following could explain the function of your gene?
Your new gene could encode a tyrosine phosphatase that isresponsible for inactivating the tyrosine kinase receptor
Your new gene could encode a protein that inhibits theactivation of the protein ras
Your new gene could encode a protein that inhibits any of theMAP kinase proteins (Raf, Mek or Erk).
All of the above

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1 c Proteins that contain a NLS interact with a transport system that is powered by the hydrolysis of GTP Proteins gain entry into the nucleus through the nuclear envelope The nuclear envelope consists of concentric See Answer

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		Your new gene could encode a tyrosine phosphatase that isresponsible for inactivating the tyrosine kinase receptor
		Your new gene could encode a protein that inhibits theactivation of the protein ras
		Your new gene could encode a protein that inhibits any of theMAP kinase proteins (Raf, Mek or Erk).
		All of the above