In D. melanogaster, a homozygous female with mutations for vestigial wings (vg), black body (b) and purple...

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Biology

In D.melanogaster, a homozygous female with mutations for vestigialwings (vg), black body (b) and purple eye color(pr) was mated to a homozygous wild-type male. All theF1 progeny, both male and female, had normal (wild-type)phenotypes for the three characteristics, indicating that themutations are autosomal recessive. In a testcross of theF1 females with males that have vestigial wings, blackbody and purple eyes, the progeny were of eight differentphenotypes reflecting eight different genotypes. The order in whichthe genes are list below is completely arbitrary.

                                   vg     b      pr   1779

                                   vg+    b+    pr+ 1654

                                   vg+    b     pr   252

                                   vg     b+    pr+ 241

                                   vg+    b     pr+ 131

                                   vg     b+    pr     118

                                   vg     b     pr+      13

                                   vg+    b+    pr        9

                                                           4197 Total

a. Determine thelinear order of the genes on the chromosome (which gene is in themiddle)?

b. Calculate therecombinant frequency between the three loci.

c. Draw a geneticmap of the three loci, with the correct map distance betweeneach.

Answer & Explanation Solved by verified expert
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P generation vg b pr vg b pr X vg bpr vg b prF1 offsprings vg b pr vg bpr phenotype wild typeTestcross vg b pr vg b prX vg b pr vg b prIn the test cross results we can observe that majority of theoffsprings have character combinations that is similar to one ofthe parents This is because the genes are linked within achromosome and therefore they are not assorting independently intheir offspring However we can also observe progenies with acombination of characters not shown by any of the parents This isdue to recombination Recombination is essentially an exchange ofgenetic information among homologous chromosomes by means ofcrossing over in the process of gamete production through meiosisProgenies that    See Answer
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