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If you want to identify genes that change expression levels in a mouse model of liver...

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Biology

If you want to identify genes that change expression levels in amouse model of liver disease under conditions of stress.

(i) What kind of DNA library will be the bestone to use and why?

(ii) Based upon your answer, design anexperiment which would allow you to identify genes which changeexpression in the liver in response to a hepatitis infection. Besure to include experimental parameters such as sample source,preparation, conditions, methods, controls, analysis, expectedresults.

Answer & Explanation Solved by verified expert
3.9 Ratings (437 Votes)
AnswerIcDNA library will be suitable one to use as it provides the expression of the liver cells and a large quantity of RNA samples can be used for quantitation Answer2 sample sourceMale mice and trangenic mouse suffereing from    See Answer
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