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In cases of renal failure, plasma (extracellular) concentrations of K+ may increase from normal levels of...

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Medical Sciences

In cases of renal failure, plasma (extracellular) concentrationsof K+ may increase from normal levels of 4-5 mM. From what you knowof the effects of increasing extracellular K+ on the membranepotential and the effects of membrane potential on the HCN channel,you would expect the increased extracellular concentration of K+to:

a. decrease heart rate

b. decrease cardiac output

c. depolarize the resting membrane potential in the pacemakercells

d. all of the above are correct

e. only a and b are correct

Answer & Explanation Solved by verified expert
3.9 Ratings (441 Votes)
DAll are correct Hyperkalemia is the state of the serum potassium level 5MmL Here it occurs due to decreasesd excretion of the K by kidneys due to renal failure and Extracellular shift of K ions As the extracellular K ion concentration increases there will be    See Answer
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