How does binding of a ligand (such as epinephrine) activate a G protein coupled receptor?The...

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How does binding of a ligand (such as epinephrine) activate a G protein coupled receptor?The ligand binds to the alpha subunit of the G protein and induces release of GDP.The ligand phosphorylates the G-protein coupled receptor.Ligand binding causes dimerization of G protein coupled receptors.Ligand binding induces a conformation change in the cytosolic domain of the receptor.

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