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How do CD4 and CD8 coreceptors facilitate signaling through the TCR?

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Biology

Howdo CD4 and CD8 coreceptors facilitate signaling through theTCR?

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The CD8 and CD4 cells increase signaling of T cells by attaching to the MHC I CD8 or MHC II CD4 molecules on the APCs The contact of the CD4 molecule with MHC II significantly decreases the number of antigenic peptides necessary for T cell activation and significantly    See Answer
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