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A 65 kg, 34-year-old epileptic patient is receiving 300 mg phenytoin daily for epilepsy. Her albumin...

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Medical Sciences

A 65 kg, 34-year-old epileptic patient is receiving 300 mgphenytoin daily for epilepsy. Her albumin is 2.4 g/dL andcreatinine clearance is 79 ml/min. After three weeks of therapy,the total phenytoin concentration is 8.5 mg/L. What is therecommended new phenytoin dose to achieve a therapeuticconcentration of 10 - 20 mg/L?

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4.2 Ratings (663 Votes)
Answer Albumin to Creatinine ratio normallyis around 30Calculate creatinine amount in theurine by the following formulaCreatinine Clearance 140 agex weight 72 x serumCr x 085Age 34 yearsWeight 65 KgCreatinine    See Answer
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