18. How can E. coli host cells be engineered so that complex proteins with a large...

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Biology

18. How can E. coli host cells be engineered sothat complex proteins with a large number of disulfide bonds areproperly folded and therefore produced in an active form ratherthan as part of an inclusion body?

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Some of the available strategies for ensuring formation of properly folded disulfidebonded proteins in bacteria such as E coli are Periplasmic expression The periplasm is an oxidizing compartment    See Answer
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