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You’re provided a lab protocol to perform a very short digestion of eukaryotic chromatin with micrococcal...

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Biology


You’re provided a lab protocol to perform a very shortdigestion of eukaryotic chromatin with micrococcal nuclease, whichshould result in DNA fragments of 200 base pairs. You setup theexperiment but get called away suddenly and are gone for a lengthof time. When you return to complete the experiment and run the gelto visualize the samples, it shows 146 base pair fragments. Explainwhat occurred.

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DNA present in chromosome in form of nucleosome coild around histone protein Each nucleosome consist of core histone and DNA present around them 200bp of DNA associated with one nucleosome out    See Answer
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