You are studying myosin V, a class of myosin which can be used in cells to...

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Biology

You are studying myosin V, a class of myosin which can be usedin cells to transport vesicles by â€œwalkingâ€ along actin filaments,towards the plus ends of these filaments. You have identified amutation in the gene for myosin V that affects its ATP bindingsite. This mutant myosin V (M) can still perform the entirecross-bridge cycle, but it takes much longer to hydrolyze ATPcompared to a wild type myosin V (W).
a) Would the duration of the cross-bridge cycle be longer in Mor W?Explain?
b) Would the duty cycle (the proportion of the cross-bridgecycle in which myosin is bound to actin) be longer in M orW?Explain?
c) How would this difference in duty cycle affect the ability ofM to transport a vesicle along an actin filament? Explain.

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3.9 Ratings (472 Votes)

The duration of the cross bridge is greater or longer in M as compared to W Head of the myosin linked or bind the actin and pulls the actin filaments towards inwards resulting in the contraction of muscles This myosin has also the ATP hydrolysing property which See Answer

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