When the chickenpox vaccine was developed older people who hadnot had chickenpox were among the first to be able to get thevaccine. However, sometimes people have such a minor chickenpoxinfection that it goes unnoticed, yet still generates completeadaptive immunity. Before giving the vaccine, healthcare workerswould test potential recipients to see if they already hadchickenpox and had immunity to the virus. Describe how you coulddevelop an ELISA test to determine if someone had immunity tochickenpox. Explain the sources of antigens, antibodies, type ofELISA, and expected results for positive and negative cases.
