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What are the four factors to consider when deciding whether a reaction proceeds via an SN1...

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Chemistry

What are the four factors to consider whendeciding whether a reaction proceeds via an SN1 oran SN2 reaction mechanism? Howdoes each factor play a role?

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4.0 Ratings (788 Votes)

1. substrate:

for sn2 mechanism, the order of substrates are 10 > 20> 30

for sn1 mechanism the reactivity order of substrate is 30 > 20 > 10.

2. nature of leaving group:

conjugate base of weak acid is the good leaving group in sn2 & sn2

3. nature of nucleophile:

strong nucleophiles favors sn2 mechanism

weak / moderate nucleophiles favours sn1 mechanism.

4. solvent

polar protic solvents favours sn1 mechanism

polar aprotic solvents favours sn2 mechanism.
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