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What are some major differences between making transgenic mice by microinjection and creating knockout mice by...

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Biology

What are some major differences between making transgenic miceby microinjection and creating knockout mice by homologousrecombination (before the advent of CRISPR/Cas9 technology)?

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Answer The key difference is that knockin is targeted meaning the desired gene is inserted into a specific locus on the target genome via homologous recombination For instancein FFI    See Answer
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