Ways in which Chemical Control Agents May Affect Bacteria 1. Describe one way an antibiotic can inhibit...

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Biology

Ways in which Chemical Control Agents May AffectBacteria

1. Describe one way an antibiotic can inhibit peptidoglycansynthesis, state how that ultimately kills the bacterium, and givean example of such an antibiotic.

2. Describe one way an antibiotic can alter bacterialribosomes, state how that ultimately inhibits or kills thebacterium, and give an example of such an antibiotic.

3. Describe one way an antibiotic can interfere with bacterialDNA synthesis, state how that ultimately kills the bacterium, andgive an example of such an antibiotic.

Ways in which Bacteria May Resist Chemical Control Agent

1. Briefly describe 3 different mechanisms, as a result ofmutation or horizontal gene transfer in a bacterium, that mayenable that bacterium to resist an antibiotic

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A Chemical Control Agents that affect bacteria 1 Peptidoglycan a cell wall component is synthesized by crosslinking of its glycan strand Transglycosidases catalyze this reaction leading to formation of polymers which will then cross link to each other Penicillin binding proteins are required for the cross linking of Dalanylalanine to glycine residue in peptidoglycan synthesis as they bind DalanyDalanine residues Beta lactams are antibiotics that inhibit penicillin binding proteins The beta lactam ring present in these antibiotics has a structure similar to DalanylDalanine Hence this beta lactam ring will interact with penicillin binding proteins This prevents the interaction between DalanylDalanine with glycine Further penicillin binding proteins are sequestered and not available for peptidoglycan See Answer

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