Using biochemistry concepts and connections by Appling answer the following: Answer 1 or 2 1. Several of the...

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Biology

Using biochemistry concepts and connections by Appling answerthe following:

Answer 1 or 2

1. Several of the pathways in this module contain examples ofenzymes with opposite function controlled through reciprocalallosteric regulation. Pick an example from one of the pathwaysstudied (pentose phosphate pathway, glycolytic pathway) anddescribe how a specific allosteric effector affects two differentenzymes in an opposing manner. Your answer should also include anexplanation of why this reciprocal regulation is important for thecontrol of both pathways.

2. Pick one enzyme that is regulated by both an allostericeffector and covalent modification. The effect of the tworegulators can be the same or different (for example, both canactivate/inhibit the enzyme or one can activate while the otherinhibits). Explain the conditions that lead to each type ofregulation, how the effect of each makes metabolic sense in thecontext of the larger pathway, and why both types of regulation areneeded for this particular enzyme.

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1 Allosteric enzyme is an enzyme that when binds to a particular allosteric modulator changes its conformation for a ligand binding site to which the ensyme originlly binds One example of the allosteric enzyme in the glycolytic pathway is the Phosphofructokinse I This enzyme catalyses one of the most important conversion in the pathwayie conversion of Fructose6phosphate to    See Answer
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