Transcription, translation and cell signaling within cells i...

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Transcription, translation and cell signaling within cells iscontrolle...

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Mutations are sudden and heritable changes in the DNA sequence there are different kinds of mutations like frameshift mutation missense mutation nonsense mutation silent mutation etc Missense mutation change in one nucleotide of the DNA sequence that changes the codon to another codon the new codon codes for another amino acid missense mutations can have deleterious effects or no effects if one amino acid at the active site of an enzyme is replaced with another amino acid with different properties it can abolish the function of the protein but if one amino acid is replaced with another amino acid of similar property it may not affect the proteins function so the effect of missense mutation depends on its location and the properties of 2 amino acids Nonsense mutation point mutation which changes the codon to a stop codon so truncated proteins are produced due to nonsense mutation the nonsense mutation results in a truncated protein if the mutation occurs at the beginning of the protein it abolishes the protein function the severity of the nonsense mutation depends on the location if the mutation occurs at one amino acid before the last amino acid then it wont affect the protein function much Frameshift mutation are due to insertion or deletion of nucleotides which are not in the multiples of three it changes the reading frame from that point so the amino acid sequence from that point changes since the amino acid sequence from the point of mutation ....

Transcription, translation and cell signaling within cells is controlled by many different mechanisms. All of this information...

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