Tony had his thyroid gland surgically removed when he was in hislate twenties; now he is in his sixties. He takes Synthroid(thyroxine) pills daily and periodically has his blood levelschecked for T4 and TSH.

Answer the following questions (1 pt each):

A. What would be some of Tony’s symptoms if he did not take hismedication?

B. What would be some of Tony’s symptoms if he took an overdoseof these pills over an extended period of time?

C. Define hydrophilic and hydrophobic. What about the chemicalstructure of a hormone makes it hydrophilic or hydrophobic?

D. How does being hydrophobic or hydrophilic affect theproduction and release, transport, and action of a hormone?

E. Is thyroxine hydrophilic or hydrophobic? How is that relatedto whether or not Tony could take it as a pill (orally) instead ofhaving to inject it?

F. What does the abbreviation T4 stand for? What does thishormone do?

G. What does the abbreviation TSH stand for? What does thishormone do?

H. How does the thyroxine in his pills affect his blood levelsof TSH?

I. If the dose of his thyroxine pills is too low, what wouldhappen to his blood levels of T4 and TSH?  

J. If the dose of his thyroxine pills is too high, what wouldhappen to his blood levels of T4 and TSH?