Tony had his thyroid gland surgically removed when he was in his late twenties; now he...

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Medical Sciences

Tony had his thyroid gland surgically removed when he was in hislate twenties; now he is in his sixties. He takes Synthroid(thyroxine) pills daily and periodically has his blood levelschecked for T4 and TSH.
E. Is thyroxine hydrophilic or hydrophobic? How is that relatedto whether or not Tony could take it as a pill (orally) instead ofhaving to inject it?
H. How does the thyroxine in his pills affect his blood levelsof TSH?
I. If the dose of his thyroxine pills is too low, what wouldhappen to his blood levels of T4 and TSH?Â Â
J. If the dose of his thyroxine pills is too high, what wouldhappen to his blood levels of T4 and TSH?

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Ans E The thyroxine is hydrophobic because it is lipid soluble Since it is hydrophobic in nature it is easily able to diffuse through the plasma membrane and hence can interact with the receptors present intracellularly Since the plasma membrane has lipid bilayer made of phospholipid it can See Answer

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