The risk of tumor metastasis can be assessed by examining gene expression, signal cascade activity, or...

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Biology

The risk of tumor metastasis can be assessed by examining geneexpression, signal cascade activity, or protein expressions ofpathological sections. Imagine an adenoma (formed by epithelialcells, non-metastatic yet) next to mesenchymal stromal cells,indicate whether the following situations would promote or inhibitor N/D (not able to determine) the metastasis of the adenoma (usethose words). (10 pts)
Expression of TGF-ï¢ RNA in adenoma
Expression of BMP RNA in adenoma
Expression of vimentin protein in adenoma
Expression of Cox-2 in stromal cells
Nuclear localization of ï¢-catenin in adenoma
Activation of TGF-ï¢ signal cascade in adenoma
Activation of TGF-ï¢ signal cascade in stromal cells
Expression of E-cadherin in carcinoma epithelia
Expression Snail in adenoma
Expression of Snail in stromalcellsÂ Â Â Â Â Â Â Â Â Â Â Â

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4.5 Ratings (651 Votes)

Expression of TGF RNA in adenoma cause metastasis of the adenoma suppressiveInhibits effects cytostasis differentiation apoptosis or indirectly through effects on the stroma suppression of inflammation and stromaderived mitogens Depending on the type of cancer bone morphogenetic protein BMP can See Answer

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