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The receptors for steroid hormones are located inside the cell instead of the membrane surface...

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The receptors for steroid hormones are located inside the cell instead of the membrane surface like most other signal receptors How do steroids gain access to their receptors Steroid hormones are lipid soluble so they can readily diffuse through the lipid bilayer of the cell membrane Both steroid hormones and their receptors are produced by the same cells O Steroid hormones first bind to a steroid activator and this complex is transported across the cell membrane by a steroid transport protein Steroid hormone receptors undergo conformational changes that relocate them on the membrane surface

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