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The patient was under acute renal failure for which the patient underwent renal dialysis to externally...

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Medical Sciences

The patient was under acute renal failure for which the patientunderwent renal dialysis to externally filter the blood viaosmosis. Dialysis involves the passage of arterial blood through atube with a semi-permeable outer membrane. This membrane onlyallows ions/metabolites/electrolytes and water to pass through.Surrounding the tube is another larger tubing containing dialysate(assume pure water). Answer the following questions regardingosmosis and the function that dialysis serves in this case.

a.In which direction is the driving force for osmosisduring dialysis and why?

b.How would the initial driving force for osmosis change(increase/decrease) if dialysis was performed less frequently?Why?

c.In this patient, blood urea nitrogen (BUN) wasmeasured at 23 mg/dl upon admission. Calculate the diffusion rate(J) of BUN across the dialysis membrane, assuming thefollowing:

Purea(membrane) = 1.5 x 10-6 cm/sec

[BUN]dialysate= 0 at t=0

Membrane thickness = 40 μm

Amembrane = 1.5 m2

d.Describe how BUN will change in the blood followingdialysis. Justify your answer.

Answer & Explanation Solved by verified expert
4.4 Ratings (669 Votes)
AThe driving force for the osmosis during dialysis is from the tube with semipermeable membranecontaining patients blood to the larger tube containing pure water    See Answer
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