The LDL receptor is a cell-surface protein receptor that allows certain cells to pull lipoproteins...
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The LDL receptor is a cell-surface protein receptor that allows certain cells to pull lipoproteins containing cholesterol out of the bloodstream into their cytoplasm. All of the following are likely true concerning the LDL receptor EXCEPT (A) it matures in the Golgi before being transported to the cell membrane within secretory vesicles. (B) its production is upregulated in the presence of higher levels of cholesterol in the blood. (C) it has polar and non-polar amino acid regions for placement within the cell membrane. (D) the receptor protein contains ER- retention signals in order to be pulled back into the cell once bound to blood lipoproteins. (E) mutations in the receptor can result in receptors that are synthesized correctly in the ER but fail to migrate to the Golgi.
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