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The intrinsic pathway of coagulation is activated by the The intrinsic pathway of coagulation is activated...

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Medical Sciences

The intrinsic pathway of coagulation is activated by the

The intrinsic pathway of coagulation is activated by the

release of heparin from the liver.
sticking of platelets to damaged tissue.
activation of proenzymes exposed to collagen.
release of tissue factor (Factor III) by damagedendothelium.
conversion of prothrombin to thrombin.

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activation of proenzymes exposed to collagen.

The intrinsic pathway is activated through exposed endothelial collagen. Exposure to endothelial collagen leads to activation of Factor XII which becomes Factor XII A
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