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The hemoglobin B gene (Hb) has a common allele (A) of SNP (rs 332) that encodes...

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Biology

The hemoglobin B gene (Hb) has a common allele (A) ofSNP (rs 332) that encodes the HbA form of (adulthemoglobin) and a rare allele (T) that encodes the sickling form ofhemoglobin, HbS. Among 571 members of the Yoruba tribein Nigeria, 440 were A/A. 129 were A/T, and 2 were T/T individuals.Use the chi-square test to determine whether these observedgenotypic frequencies fit the Hardy-Weinberg expectations.

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