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The first person in the family represented by the pedigree shown here who exihibited symptoms...

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The first person in the family represented by the pedigree shown here who exihibited symptoms of the mitochondrial disease MERRF was II 2 Check all possible explanations of why the mother 1 1 was unaffected but her daughter I1 2 was affected I Check All That Apply U U 2 2 3 4 3 The father 1 2 was homoplasmic for mutant mtDNA The mother 1 1 was heteroplasmic for wild type and mutant mtDNA The father 1 2 was heteroplasmic for wild type and mutant mtDNA A spontaneous mutation occurred in the mtDNA of the mother s germ line cells A spontaneous mutation occurred in the mtDNA of the zygote that became individual 11 2

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