Tasmanian researchers conducted a case –control study to investigate the effect of dietary fat intake on...

70.2K

Verified Solution

Question

Medical Sciences

Tasmanian researchers conducted a case –control study toinvestigate the effect of dietary fat intake on skin cancer. Theyhypothesised that people whose dietary fat intake is lowwill be more susceptible to skin cancer. The studycompared 500 cases of melanoma with 500 controls who were randomlyselected from the state’s electoral roll. The researcherscategorised the dietary fat intake into three categories High,Moderate and Low. They found that among skin cancer patients 150were classified at the low and 80 at the high dietary fat intakewhereas among control 130 were at the low and 100 were at thehigh.   

  1. Build a table to summarise the data above which willhelp you estimate the association between dietary fat intake andSkin cancer
  2. , pay attention to headings of columns and rows [4points]
  1. Calculate the appropriate measure of relative risk (RR) ofhaving melanoma between those consuming low fat intake versus highfat intake; calculate the appropriated measure of RR of havingmelanoma between those consuming medium to high fat intake andexplain in words the meaning of what you found [4points].
  1. Calculate the percent attributable risk due to exposure tolow-dietary fat intake on Melanoma and explain in one or twosentences the meaning of your findings [4points]
  1. Calculated the population attributable risk of low-fat intakeon melanoma and explain in words the meaning of such finding[4 points]

e) What do you think about the conclusions of the PAR regardingexposure to low fat diet to reduce melanoma? (no more than 3-4sentences) [4 points}

Answer & Explanation Solved by verified expert
4.2 Ratings (594 Votes)
Hypothesis Low fat exposure intake leads to skin cancer outcome The date is given can be tabulated as follows Case Control Total High 80 100 180 Medium 270 270 540 Low 150 130 280 Total 500 500 1000 Answer a part 1 The relative risk of developing melanoma in a patient with low fat intake vs high fat can be calculated as follows 2 x 2 table Case Melanoma Control Total low exposed a150 b130 ab280 High nonexposed c80 d100 c d180 Total ac 230 bd 230 abcd460 the formula for relative risk it is the ratio of the probability of an outcome in the exposed group to the probability of an outcome in the nonexposed group therefore relative risk aab ccd 150 150 130 80 80 100 150 280 80 180 053 044 12 Interpretation If    See Answer
Get Answers to Unlimited Questions

Join us to gain access to millions of questions and expert answers. Enjoy exclusive benefits tailored just for you!

Membership Benefits:
  • Unlimited Question Access with detailed Answers
  • Zin AI - 3 Million Words
  • 10 Dall-E 3 Images
  • 20 Plot Generations
  • Conversation with Dialogue Memory
  • No Ads, Ever!
  • Access to Our Best AI Platform: Flex AI - Your personal assistant for all your inquiries!
Become a Member

Other questions asked by students