Stimulated B lymphocytes switch from the synthesis of membrane-bound to secreted antibody molecules by increasing the concentration...

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Biology

Stimulated B lymphocytes switch from the synthesis ofmembrane-bound to secreted antibody molecules by increasing theconcentration of CstF complexes that cleave and polyadenylatemRNAs. How does this up-regulation of CstF bring about theproduction of soluble antibodies?

It favors a strong polyadenylation site in the immunoglobulinprimary transcript, creating a longer antibody molecule that issecreted.

It activates a weak polyadenylation site in the immunoglobulinprimary transcript and prevents splicing, creating a shortermolecule that is secreted.

It favors a strong polyadenylation site in the immunoglobulinprimary transcript, creating a shorter antibody molecule that issecreted.

It activates a weak polyadenylation site in the immunoglobulinprimary transcript, creating a longer antibody molecule that issecreted.

It favors a strong polyadenylation site in the immunoglobulinprimary transcript, aborting translation and creating a shorterantibody molecule that is secreted.

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The Bcell antibodies are initially present as membranebound receptors They have a hydrophobic segment that leads to their incorporation into the membrane These receptors initially function in    See Answer
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