Some pharmaceuticals were much more commonly prescribed at one time but today are prescribed much less...

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Medical Sciences

Some pharmaceuticals were much more commonly prescribed at onetime but today are prescribed much less frequently. Pick two suchsubstances and explain the dramatic decline in psychiatric use. Beas specific and as detailed as you can.
use Goode's book and tell page number

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1MAOImonoamine oxidase inhibitor were once commonly prescribed between 19501970 as treatment of majordepressive disorderparticularly treatment resistant depression and atypical depressionThey are powerful antidepressantsas well as effective therapeutic agents for panic disorder and social phobiaThey are also used in the treatment of Parkinsons disease and several other disorders But they have numerous side effects in relation to dietary limitations and drug interactions some of which can be fatal People taking MAOIs generally need to change their diets to limit or avoid foods and beverages containing tyramine If large amounts of tyramine are consumed they may suffer hypertensive crisis which can be fatal Examples of foods and beverages with potentially high levels of tyramine include animal liver and fermented substances such as alcoholic beverages and aged cheesesExcessive concentrations of tyramine in blood plasma See Answer

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