Sodium-coupled transport is an important way of moving molecules in and out of the cell. Cardiac...

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Biology

Sodium-coupled transport is an important way of moving moleculesin and out of the cell. Cardiac cells have a transporter for bothNa+ and Ca+2; for every 3 Na+ that come into the cell, 1 Ca+2 isexported out of the cell. Ouabain is a drug that inhibits the Na/Kpump. Explain what would happen to Na+, K+ and Ca+2 if ouabain wasadded to cardiac cells (for simplicityâ€™s sake, consider that theonly two transporters involved are the Na/K pump and the Na/Cacotransporter).

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The sodium potassium ATPase pump will transport 3 sodium ions out of the cell and two potassium ions inside the cell There are two conformations E1 and E2 in the functioning of NaK ATPase pump There is binding of sodium ions and ATP in E1 conformation to the NaK ATPase pump ATP is then hydrolyzed and ADP is removed while Pi remains attached This alters See Answer

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