Shown following is the first 30 amino acid (one-letter code) region of this putative amino acid...

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Biology

Shown following is the first 30 amino acid (one-letter code)region of this putative amino acid sequence for p18:
¹YFNPSÂ Â Â Â ^6TSDWPTÂ Â Â Â ¹¹LAPANÂ Â Â Â ¹⁶YTFLFÂ Â Â Â ²¹FLARYÂ Â Â Â ²⁶WYINL³⁰
A) Based on the partial amino acid sequence provided, do youthink that it is more likely that this region of p18 associateswith a cellular membrane or is exposed to the cytosol?
B) Why or why not?Â Â
C) Describe how you would experimentally demonstrate if p18 wasassociated with the membrane or the cytosol.

Answer & Explanation Solved by verified expert

3.6 Ratings (660 Votes)

A The P18 region of the protein associates with the interior of cell membrane as it has more hydrophobic amino acid Hence it will repel water B 1YFNPS 6TSDWPT11LAPAN16YTFLF21FLARY26WYINL30 The amino acid sequence in 3 lettercode is 1 TyrPheAsnProSer 6 SerAspTrpProThr 11 LeuAlaProAlaAsn 16 TyrThrPheLeuPhe 21 PheLeuAlaArgTyr 26 TrpTyr IleAsnleu 1 1 TyrPheAsnProSer Hydrophobic amino acids 3 Hydrophillic amino acid2 2 6 SerAspTrpProThr Hydrophobic amino acids 2 Hydrophillic amino acid3 3 11 LeuAlaProAlaAsn Hydrophobic amino acids 4 See Answer

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