Sex determination in Mammals. You have identified a gene that you have named â€œmont1â€ (for â€˜make ovaries...

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Sex determination in Mammals. You haveidentified a gene that you have named â€œmont1â€ (for â€˜makeovaries not testesâ€™) that is expressed at the time when thebipotential gonad becomes specified to become an ovary. Because ofthis â€œshow itâ€ evidence that mont1 is expressed in theright place at the right time, you hypothesize that mont1is a critical regulator of the female primary sex determinationpathway to specify ovary development.
From what you know about the primary sex determination pathwayfor ovary development, what signaling pathway would you predict mayactivate mont1 expression?
What â€œlose itâ€ experiment could you do to determine ifmont1 is necessary for ovary development. Briefly describethe expected result. (As in â€¦ I would do X experiment and expect tosee Y result if mont1 is necessary for ovarydevelopment).
What â€œmove itâ€ experiment could you do to determine ifmont1 is sufficient for ovary development. Brieflydescribe the expected result. (As in â€¦ I would do X experiment andexpect to see Y result if mont1 is sufficient for ovarydevelopment).

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4.3 Ratings (964 Votes)

ANSWER A The development of any organ system requires cellular signaling0 In the abscence of sry XX gomads devlop Ovaries The RSpondin 1 Wnt4 beata Catein Signaling Pathulay RSpo1 Activates Canonical beata See Answer

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Sex determination in Mammals. You have identified a gene that you have named â€œmont1â€ (for â€˜make ovaries...