Secretase family of enzymes are central to the processing of amyloid precursor proteins (APP) associated with...

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Biology

Secretase family of enzymes are central to the processing ofamyloid precursor proteins (APP) associated with the development ofAlzheimer's disease. They have garnered much attention over theyears as a possible therapeutic target for the disease. Wouldtargeting these enzymes for inhibition be an effective strategy forpreventing the onset of Alzheimer's related amyloid plaqueformation. If not, can you think of another approach that might beeffective that doesn't necessarily involve targeting theseenzymes?
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Amyloid plaques formation is the common event in Alzheimers disease There are number of evidences observed that an A peptide polypeptide or amyloid form which is an oligomer responsible for the damages caused in Alzheimers disease The A plaques damages the neural cells of the brain and inactivate the required cell communications and activate the immune cells which leads to inflammation There are 3 important proteases enzymes such as secretase See Answer

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