Scientists were successful in creating Dolly the sheep using the nucleus isolated from a differentiated cell...

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Biology

Scientists were successful in creating Dolly the sheep using thenucleus isolated from a differentiated cell from an adult mammarygland. They transferred this nucleus to an enucleated egg andactivated the egg to start development. Thus, the adult mammarygland nucleus could replace the nucleus created in the 1 cellzygote from the fusion of the egg and sperm genetic material. Wow!It's amazing that this works!

1) Describe in your own words how the success of reproductivecloning is able to demonstrate \"genomic equivalence\".

2) BUT....While this technique was successful in creating Dolly(and in a wide array of other species), it has a notoriously lowsuccess rate. Ignoring all of the technical reasons why this couldfail (meaning ignoring all of the \"scientist user error\"), explainhow the contents of the nucleus can contain the same geneticsequence but still not be functionally equivalent to the 1 cellzygote nucleus. What might be different between a mature nucleusand a zygote nucleus that results in the low success rate?

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3.6 Ratings (448 Votes)
1 according to genomic equivalence principal all cells carry the same genetic information as carried by the single zygotic cell to encode an organism In the dolly sheep example mature somatic cell nucleus encoded all information required for the full organism    See Answer
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