Regarding countercurrent mechanisms: List which structure(s) is/are responsible for establishing the concentration gradient in the renal medulla?...

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Medical Sciences

  1. Regarding countercurrent mechanisms:
    1. List which structure(s) is/are responsible for establishing theconcentration gradient in the renal medulla? Describe how this isaccomplished. (5 points)
      1. Note: You do not need to describe the entire positivefeedback loop, I am looking more simply for structures orstructural modifications and functions of those structures. Domention how the tubular fluid concentration changes and theinterstitial fluid of the medulla is affected as aresult.
    2. List which structure(s) is/are responsible for maintaining theconcentration gradient in the renal medulla? Describe how this isaccomplished. (2 points)
    3. ACE inhibitors (angiotensin converting enzyme inhibitors) are apopular class of drug that treats hypertension. Use your knowledgeof the renin-angiotensin-aldosterone system to describe thephysiological mechanism of how this medication works at the nephronand kidney level to reduce blood pressure. (3 points)
    4. Predict how ADH hypersecretion would affect the sodiumconcentration of the urine, and explain why. (2 points)

Answer & Explanation Solved by verified expert
4.0 Ratings (574 Votes)
a The descending and ascending loop and vasa recta form a countercurrent multiplier system this is known as countercurrent mechanism because Descending and asscending limb goes in opposite direction the basic mechanism involved is that the asscending limb reabsorbs ion like sodium potassium and chlorine which will make the medula hypertonic salty this in turn will make the descending limb absorb water    See Answer
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