Red-green color blindness is caused by a mutation in a gene onthe X chromosome. Xa is the recessive mutant allele thatcauses color blindness; XA is the dominant, functionalallele. You meet a patient who has Klinefelter syndrome (that is,he has an XXY karyotype). His mother is colorblind, but his father has normal colorvision. Your patient has both the XAand the Xa alleles.
- You hypothesize that your patient’s syndrome is due to ameiotic nondisjunction event that occurred in: (circle the correctoptions) (2 pts)
thispatient                thispatient’sfather              thispatient’s mother
                                                MeiosisI         or        MeiosisII
- In the space provided below, illustrate how the meioticnondisjunction event occurred, showing only the sexchromosomes. If you think it could happen in either meiosis I orII, pick one of these for illustration. (6pts)
- Use the symbols below to illustrate the X and Ychromosomes:
- Use arrow(s) to indicate the cell(s) that could give rise toyour patient’s abnormal karyotype.
- You also find a small number of cells in this patient with onlyone X and one Y chromosome. Explain this phenomenon in no more thantwo sentences. Be specific about in whichindividual and roughly when this relevantevent might have taken place. (2 pts)