Receptor binding motifs such as RGD have highly selective recognition for cell adhesion. Outline a strategy...

60.1K

Verified Solution

Question

Biology

Receptor binding motifs such as RGD have highly selectiverecognition for cell adhesion. Outline a strategy for incorporatinga cell adhesion. Outline a strategy for incorporating a celladhesion recognition domain to a biomaterial. Address the problemssurrounding domain quantity, type and affinity in yourdiscussion.

Answer & Explanation Solved by verified expert

4.0 Ratings (605 Votes)

RGD is a tri amino acid peptide made up of ArginineGlycineAspartate It is most commonly used adhesive peptide which is much effective in attaching various cell tyoes to plethora of biomaterials Extracellular matrix proteins such as integrins osteopontin fibrinogen fibronectin bone sialoproteina nd vibronectin alongwith collagens and laminins contains a prime binding domain that is RGD Thus the artificial peptide RGD can bind to many integrin species Due to this recognition benefit the artificial RGD maintains its functionality during the sterilization and processing steos of biomaterial synthesis Again this property nominalises the immne See Answer

Get Answers to Unlimited Questions

Join us to gain access to millions of questions and expert answers. Enjoy exclusive benefits tailored just for you!

Membership Benefits:

Unlimited Question Access with detailed Answers
Zin AI - 3 Million Words
10 Dall-E 3 Images
20 Plot Generations
Conversation with Dialogue Memory
No Ads, Ever!
Access to Our Best AI Platform: Flex AI - Your personal assistant for all your inquiries!

Become a Member