Question 9 [11 marks / 11 minutes] This question is about regulation of expression of the...

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Biology

Question 9 [11 marks / 11 minutes]
This question is about regulation of expression of the trp operonby control of attenuation. Assume there are intermediate levels oftryptophan, such that TrpR (the repressor protein) isinactive.
a)Design a mutation within the 5â€™ UTR of the trp operon that wouldgive the outcome below.Explain how your mutation would result inthat outcome.
i.increased expression of the operon relative to wildtype[4marks]
ii.decreased expression of the operon relative to wildtype[4marks]
b)Predict and explain the effect of insertion of T-A basepairsimmediately after region 3, such thaturacils are transcribed.Assume this insertion does not change the ability of regions 1, 2,3 or 4to form stem-loop structures. [3 marks]

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Please find the answers below The trp operon is a repressible operon which undergoes decline in gene expression under the presence of substrate ie tryptophan As a mechanism the presence of tryptophan causes formation of a stemloop structure in the operon which prevents See Answer

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