Question 156 Which of the following is not among the 4 most commonly mutated genes in pancreatic...

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Biology

Question 156
Which of the following is not among the 4 most commonly mutatedgenes in pancreatic cancer?
KRAS
p16 gene
TGFb eta
SMAD4
Question 164
Pancreatic Ductal Adenocarcinoma (PDAC) tumors typically arisefrom (choose all that apply):
tumorigenic pancreatic stellate cells
neoplasms derived from ductal cells
neuroendocrine cells
grade 3 intraepithelial neoplasms
Question 170
A drug that inhibits the interaction between PD and PDL-1 wouldbe classified as a(n)
NSAID
checkpoint inhibitor
adoptive cell transfer inhibitor
cytokine-mediated chemotherapeutic agent
Question 60
Chronic inflammation has been observed to play a role inpromoting which of the following?
tumor cell proliferation
tumor cell genetic mutations
angiogenesis
metastasis
All of the above.
Question 73
Which of the following is not a common symptom of pancreaticcancer?
lower back pain
jaundice
bloody stools
diabetes
obstructed bile duct
Question 82
CD8+ and CD4+ activation can be inhibited when ______________ ontumor cells cause:
MHC receptors ; a downregulation of Programmed Death (PD)ligand expression on T cell membranes
Programmed death ligand (PDL-1) molecules ; a downregulation ofAkt/PI3K-mediated growth/proliferation
T cell ; the activation of NK cells
None of the above.

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Q156 KRAS oncogene especially KRAS2 is responsible for pancreatic cancer about in 90 of cases This gene is located in the chromosome arm 12p and functions as a GTPase involved in intracellular See Answer

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