Q:Find and summarize one specific application of IPCSs in bone tissue engineering. Your summary should include...

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Medical Sciences

Q:Find and summarize one specific application of IPCSs in bonetissue engineering. Your summary should include scaffoldcharacteristics, scaffold manufacturing technique, developmentprocess of Induced Pluripotent Stem Cells (IPSCs), how IPSCsresponse to these scaffolds, differentiation characteristics ofIPCSc, how osteogenic differentiation is evaluated and generalcomments about potential usage of IPSCs in bone tissue engineeringapplications? Please do not forget to state your reference articleor resource. (Note that it could be a tissue engineering textbook.)

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Induced pluripotent stem cells iPSCs reprogrammed from adult somatic cells using defined transcription factors are regarded as a promising cell source for tissue engineering For the purpose of bone tissue regeneration efficient in vitro differentiation of iPSCs into downstream cells such as mesenchymal stem cells MSCs osteoblasts or osteocytelike cells before use is necessary to limit undesired tumorogenesis associated with the pluripotency of iPSCs Until    See Answer
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