Q8. [10 marks] Many molecules are involved in providing stability to the Pre-Initiation Complex (PIC) in eukaryotes. Describe: The...

50.1K

Verified Solution

Question

Biology

Q8. [10 marks]
Many molecules are involved inproviding stability to the Pre-Initiation Complex (PIC) ineukaryotes. Describe:
The steps involved in stimulating initiation of transcriptionfrom a silent gene
How the molecules interact to provide stability to the PIC
How the polymerase escapes from this PIC to allow thetranscript to elongate

Answer & Explanation Solved by verified expert

3.8 Ratings (753 Votes)

a The preinitiation complex PIC is a large complex of proteins necessary for gene transcription in eukaryotes and archaea The PIC aids in the correct positioning of RNA polymerase II on the transcription start site produces DNA denaturation and places DNA at the active site of RNA polymerase II for transcription to occur This complex is normally composed of six general transcription factors TFIIA TFIIB TFIID TFIIE TFIIF and TFIIH In 2007 Roger D Kornberg proposed the See Answer

Get Answers to Unlimited Questions

Join us to gain access to millions of questions and expert answers. Enjoy exclusive benefits tailored just for you!

Membership Benefits:

Unlimited Question Access with detailed Answers
Zin AI - 3 Million Words
10 Dall-E 3 Images
20 Plot Generations
Conversation with Dialogue Memory
No Ads, Ever!
Access to Our Best AI Platform: Flex AI - Your personal assistant for all your inquiries!

Become a Member