Previous studies have shown that Alzheimer's patients who also take beta-blockers tend to see a slower...

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Psychology

Previous studies have shown that Alzheimer's patients who alsotake beta-blockers tend to see a slower decline in their mentalfunction.
Â Â Â Â Â Â Â Â Â Â Â a) Why would overstimulation of AMPA receptors cause short-termmemory deficits?
Â Â Â Â Â Â Â Â Â Â Â b) Alzheimerâ€™s is associated with neuron death. Why wouldoverstimulation of AMPA receptors cause neurons to die?
Â Â Â Â Â Â Â Â Â Â Â c) Previous studies had found that blocking the AMPA receptoralleviates the misfiring caused by amyloid plaques in the brain.Why wouldnâ€™t it be a useful strategy to treat Alzheimerâ€™s with AMPAreceptor antagonists?
Â Â Â Â Â Â Â Â Â Â Â d) Why might heart-disease/blood pressure medication work to slowdown the decline of people with Alzheimerâ€™s

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a Overstimulation of AMPA receptors cause shortterm memory deficits as it creates a situation called Excitotoxity This refers to damaged nerve cells due to excessive stimulation by neurotransmitters The AMPA gets overstimulated and overactivated due to this excitotoxity A high level of calcium enter the cells and this leads to secretion of See Answer

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