Logo
Home Study Material Contact Search
AI Chat FREE
  1. sciences
  2. biology
  3. please explain with details!!! thank you! 3. cons

Please explain with details!!! THANK YOU! 3. Consider the following normal sequence: Gly-leu-arg-gln-cys-ile-phe And the following mutant proteins. What...

90.2K

Verified Solution

Question

Biology

Please explain with details!!! THANK YOU!

3.

  1. Consider the following normal sequence:

Gly-leu-arg-gln-cys-ile-phe

And the following mutant proteins. What is the nature of eachmutation? Describe what happens in each case.

  1. Gly-leu-arg-gln                     
  2. Gly-leu-arg-arg-cys-ile-phe
  3. Gly-phe-lys-thr-met-gln-ile
  1. Epidermolytic hyperkeratosis is an autosomal dominant conditionthat produces scaly skin. It can be caused by a missense mutationthat substitutes a histidine (his) amino acid with an arginine(arg). Write the mRNA codons that could account for this change,and indicate if it is a transition or transversion.

c. Individuals with mutations in the GJB2 gene are deaf. Themost common mutation in a population is a deletion of this gene’s235th nucleotide, which is a C. The normal GJB2 proteinis made in the cytoplasm and then moves to the cell membrane. Inpatients with the most common mutant allele, the GJB2 proteinremains in the cytoplasm and is quickly degraded. This mutation islikely classified as a:

  1. Missense mutation
  2. Nonsense mutation
  3. Gain-of-function mutation
  4. Loss-of-function mutation

Answer & Explanation Solved by verified expert
4.2 Ratings (867 Votes)
Answer 3a In this question normal and manymutant sequence are given Explanation is given blowb In    See Answer
Get Answers to Unlimited Questions

Join us to gain access to millions of questions and expert answers. Enjoy exclusive benefits tailored just for you!

Membership Benefits:
  • Unlimited Question Access with detailed Answers
  • Zin AI - 3 Million Words
  • 10 Dall-E 3 Images
  • 20 Plot Generations
  • Conversation with Dialogue Memory
  • No Ads, Ever!
  • Access to Our Best AI Platform: Flex AI - Your personal assistant for all your inquiries!
Become a Member

Other questions asked by students

Finance
1.2K views

1) Describe two signals, one pro, one con, a company may send to the markets when...

Medical Sciences
1.2K views

Dr. Green is studying the role of rods in vision. Dr. Green applies a K+ channel...

Basic Math
1.2K views

Avoiding an accident while driving can depend on reaction time. That time, measured from the time...

Biology
1.2K views

Soln Today let s talk about horses and their cool trick the stay apparatus in...

Geometry
1.2K views

E B F In the figure ABCD is a lattice and AEFG is a square...

Calculus
1.2K views

Find the derivative of the function g x

Algebra
1.2K views

Question 10 Given the graph of the ellipse determine its equation 5 4 3 2...

Accounting
1.2K views

Berj Corporation issued bonds and received cash in full for the issue price. The bonds...

Accounting
1.2K views

In 2024, the Westgate Construction Company entered into a contract to construct a road for...

Accounting
1.2K views

Why do we need the employee's date of birth in order to calculate pay? Select...

Accounting
1.2K views

Sales: quarter 1,28,600 bags; quarter 2,42,800 bags. Selling price is $63 per bag. ...

Finance
1.2K views

Use the Black-Scholes model to value a call option with the following data: Price $32...