Patients with uncontrolled diabetes may enter a state called diabetic ketoacidosis, a form of metabolic acidosis...

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Patients with uncontrolled diabetes may enter a state calleddiabetic ketoacidosis, a form of metabolic acidosis in which lowblood pH is caused by the excessive accumulation of acidic ketonebodies in the blood, due to excessive catabolism of stored fats(NOTE: while not relevant to this question, it might be interestingand a good review to make sure you understand why impaired insulinsignaling would cause this to occur!). If this acidosis becomessevere and life-threatening, patients will eventually exhibitKussmaul breathing: very deep, rapid, gasping breaths. which of thefollowing scenarios explains why that is the case?

A Low blood pH increases the firing rate of central andperipheral chemoreceptors which increases the bursting rate ofbrainstem respiratory rhythmicity center neurons which increasesthe strength and rate of diaphragm contractions.

B Low blood pH increases the bursting rate of brainstemrespiratory rhythmicity center neurons which increases the firingrate of central and peripheral chemoreceptors which increases thestrength and rate of diaphragm contractions.

C Low blood pH decreases the bursting rate of brainstemrespiratory rhythmicity center neurons which increases the firingrate of central and peripheral chemoreceptors which decreases thestrength and rate of diaphragm contractions.

D Low blood pH increases the firing rate of central andperipheral chemoreceptors which decreases the bursting rate ofbrainstem respiratory rhythmicity center neurons which increasesthe strength and rate of diaphragm contractions. E Low blood pHdecreases the firing rate of central and peripheral chemoreceptorswhich increases the bursting rate of brainstem respiratoryrhythmicity center neurons which decreases the strength and rate ofdiaphragm contractions.

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AnswerA Low blood pH increases the firing rate of central and peripheral chemoreceptors which increases the bursting rate of brainstem respiratory rhythmicity center neurons which increases the    See Answer
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