Patients with uncontrolled diabetes may enter a state calleddiabetic ketoacidosis, a form of metabolic acidosis in which lowblood pH is caused by the excessive accumulation of acidic ketonebodies in the blood, due to excessive catabolism of stored fats(NOTE: while not relevant to this question, it might be interestingand a good review to make sure you understand why impaired insulinsignaling would cause this to occur!). If this acidosis becomessevere and life-threatening, patients will eventually exhibitKussmaul breathing: very deep, rapid, gasping breaths. which of thefollowing scenarios explains why that is the case?
A Low blood pH increases the firing rate of central andperipheral chemoreceptors which increases the bursting rate ofbrainstem respiratory rhythmicity center neurons which increasesthe strength and rate of diaphragm contractions.
B Low blood pH increases the bursting rate of brainstemrespiratory rhythmicity center neurons which increases the firingrate of central and peripheral chemoreceptors which increases thestrength and rate of diaphragm contractions.
C Low blood pH decreases the bursting rate of brainstemrespiratory rhythmicity center neurons which increases the firingrate of central and peripheral chemoreceptors which decreases thestrength and rate of diaphragm contractions.
D Low blood pH increases the firing rate of central andperipheral chemoreceptors which decreases the bursting rate ofbrainstem respiratory rhythmicity center neurons which increasesthe strength and rate of diaphragm contractions. E Low blood pHdecreases the firing rate of central and peripheral chemoreceptorswhich increases the bursting rate of brainstem respiratoryrhythmicity center neurons which decreases the strength and rate ofdiaphragm contractions.