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Patients with inflammatory bowel disease (IBD) have been shown to have gastrointestinal (GI) microbes distinct from...

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Biology

  1. Patients with inflammatory bowel disease (IBD) have been shownto have gastrointestinal (GI) microbes distinct from healthypatients that are matched for age/weight/diet and other variables.One hallmark of IBD is the leakage of IgA from the GI tract intothe bloodstream. How would you determine if the GI microbiota ofIBD patients can cause IgA leakage (in detail)? Assume that youhave access to GI microbiota samples from IBD patients and matchedhealthy controls, a colony of germ-free mice, and a blood test forIgA. (3 pts)

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In order to determine if the effect of GI microbiota on leakage of IgA into the bloodstream the following experiment needs to be done First and foremost confirm that the germfree mice    See Answer
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