Part A: Outline and paraphrase the negative feedback cycles involved in the development and maturation of sperm...

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Medical Sciences

Part A:
Outline and paraphrase the negative feedback cycles involved inthe development and maturation of sperm in the human male. Includethe role of follicle stimulating hormone(FSH), luteinizing hormone(LH), androgen binding protein (ABP)and inhibin.
Part B:
Outline and paraphrase the negative feedback cycles involved inthe development and ovulation of an egg in the female. Include therole of follicle stimulating hormone (FSH), luteinizing hormone(LH), estrogen and progesterone.

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Part A FSH Follicular stimulating hormone LH Luteinising hormone Hypothalamic controlGnRH Arcuate nuclei of the hypothalamus secrete GnRH into the hypothalamichypophysial portal blood GnRH stimulates the anterior pituitary to secrete FSH and LH Anterior pituitaryFSH and LH FSH acts on the sertoli cells in seminiferous tubules to maintain spermatogenesis The sertoli cells also secrete inhibin which help in negative feedback of FSH secretion LH acts on the Leydig cells to promote testosterone synthesis Testosterone acts via an intratesticular paracrine mechanism to increase the See Answer

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