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Outline the mechanism of the conversion of α-ketoglutarate to succinyl-CoA catalyzed by α-ketoglutarate dehydrogenase complex. Put these 5...

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Chemistry

Outline the mechanism of the conversion of α-ketoglutarate tosuccinyl-CoA catalyzed by α-ketoglutarate dehydrogenasecomplex.

Put these 5 steps in order:

1. decarboxylation

2. transacylation

3. dihydrolipoyl dehydrogenase activity

4. oxidation of 4-carbon group, reduction of lipoamidedisulfide

5. enzymatical FADH2 reoxydation by NAD+

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